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What Is Berger’s Disease?

kidneysHave you ever heard of Berger’s Disease? You may have also heard it called IgA nephropathy. It’s a type of kidney disease where the immunoglobulin A (IgA) antibody actually gets stuck in the kidneys. When this happens, that part of the kidney becomes inflamed and can cause the kidneys to either work at a diminished level. This means they may not be able to filter out waste, electrolytes, or excess water. That can lead to kidney damage. Normally, Berger’s Disease progresses fairly slowly, and it can actually be years before you know that you have it. However, it affects each person differently, and some will start to see signs of it much earlier than others. However, if it goes untreated for too long, it can eventually lead to kidney failure.

Causes

When the IgA antibody accumulates in the kidneys, they are no longer able to function quite right due to the inflammation. But what causes these deposits to build up? No one is really sure. There are a few possibilities, though:

• Those with certain genes or in specific ethnic groups may be more at risk of developing Berger’s. It’s possible this disease runs in families.
• Some liver diseases may be linked to Berger’s Disease.
• Dermatitis herpetiformis may also have a conection.
• Celia disease is another potential cause.
• Some infections may also play a part.

Men are about twice as likely to develop Berger’s Disease as women, especially in Europe and North America. Asians and Caucasians are also at higher risks.

Symptoms

If you’re dealing with Berger’s Disease, you probably won’t see any symptoms at first. In fact, it can be years or even decades before symptoms appear. If you have a urine test, that can detect the elevated red blood cell and protein that get flushed out. Here are some other signs that you need to pay attention to:

• Urine that has a brown, tea-like color to it.
• Blood visible in the urine.
• Pain in your side or lower back.
• Swelling in your feet or hands.
• High blood pressure.

Treatment

There is no cure for Berger’s Disease, and those who have it will have to deal with the symptoms rather than attacking the disease itself. Many take high blood pressure medications because the disease can raise blood pressure. Others take fish oil and eat foods that are high in Omega-3 fatty acids to reduce the inflammation.

Other treatments include taking immunosuppressants or taking Mycophenolate mofetil. Statin therapy may also help.

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These statements have not been evaluated by the FDA. These products are not intended to treat, diagnose, or cure any diseases.